Molecular technique identifies the pathogen responsible for culture negative infective endocarditis
نویسندگان
چکیده
منابع مشابه
Blood culture-negative infective endocarditis with thalassemia and neurological complication: A dangerous combination
Background: Infective endocarditis (IE) is a life-threatening systemic disease that mostly affects people with valvular heart disease, prosthetic valves, or intracardiac devices. Infective endocarditis is a dangerous cardiac involvement in thalassemia patients. Thus, a multidisciplinary approach is important to provide efficient and effective therapy. Case presentation: A 31-year-old man cam...
متن کاملCurrent issues in the diagnosis and management of blood culture-negative infective and non-infective endocarditis.
Diagnosis and management of blood culture-negative endocarditis constitute a formidable clinical challenge and a systemic approach is necessary for a successful outcome. Blood cultures are negative in endocarditis due mainly to preceding antibiotic administration or to fastidious slow-growing organisms. Less so, non-infective endocarditis is a paraneoplastic manifestation or may occur in associ...
متن کاملMolecular diagnosis of culture negative infective endocarditis: clinical validation in a group of surgically treated patients.
OBJECTIVE To assess the clinical validity of polymerase chain reaction (PCR) based molecular methods in the microbiological diagnosis of culture negative infective endocarditis in a group of surgically treated patients. DESIGN Retrospective case-control study. SETTING Reference cardiovascular surgical centre. PATIENTS AND SAMPLES: 15 culture negative patients with infective endocarditis cla...
متن کاملBlood culture-negative endocarditis
Blood culture-negative endocarditis (BCNE) may represent up to 70% of all endocarditis cases, depending on series. From 2001 to 2009, we implemented in our laboratory a multimodal diagnostic strategy for BCNE that included systematized testing of blood, and when available, valvular biopsy specimens using serological, broad range molecular, and histopathological assays. A causative microorganism...
متن کاملNegative predictive value of the Duke criteria for infective endocarditis.
With use of new Duke criteria, 405 episodes of suspected endocarditis were previously classified as "definite," "possible," or "rejected" endocarditis. To determine the negative predictive value of the Duke clinical criteria for the classification of suspected endocarditis, chart review and follow-up were performed for the 52 episodes in which the diagnosis of endocarditis was rejected. Three o...
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ژورنال
عنوان ژورنال: Heart
سال: 2005
ISSN: 1355-6037
DOI: 10.1136/hrt.2004.056762